Recent studies have shown that there is a clear link between Fosamax usage and femoral shaft fractures and osteonecrosis. The irony is that bisphosphonates such as Fosamax, which were originally prescribed to prevent bone decay, may actually be causing bone decay like femoral shaft fractures and osteonecrosis of the jaw (ONJ).
In 2006 the American Association of Endodontists felt compelled to publish a position statement about the effect of bisphosphonates on the jaw. It stated, “Therefore, until further information is available, it would appear prudent to consider all patients taking bisphosphonates to be at some risk for ONJ, with the recognition that the magnitude of the risk probably varies depending upon the particular bisphosphonate taken, patient factors (e.g., concurrent drugs, diseases, etc.), and dental treatment history.” Again, Fosamax is considered a class of bisphosphonate.